Acetyl-L-Carnitine (ALC is clearly one of the most extensively researched brain nutrients with a proven ability to enhance and revive brain and mental energy. This powerful antioxidant can cross the blood-brain barrier where it plays a role in the production of the neurotransmitter acetylcholine as well as supporting healthy blood flow to the brain.
ALC is a combination of the amino acid L-Carnitine attached to an acetyl group, thereby making ALC fat soluble so that it can cross the blood-brain barrier whereas unattached L-Carnitine clearly does not. Proper energy metabolism for the brain is vital since it makes up 20% of energy consumption. This is highly significant for ADHD (eases autistic “stimming”), Alzheimer’s, cognitive disorders, memory loss, mental fatigue, mitochondrial, neurotransmitter challenges etc.
ALC has been shown to reduce the accumulation of damaged fats in the brain and on the skin (brown spots). ALC supports healthy metabolism of fats, as well as thyroid and leptin function.
ALC is found in high concentrations in the brain, nerves, heart, muscles, liver and sperm cells. Research shows that ALC increases the natural production of both serotonin and dopamine and provides improved tolerance to stress. ALC also increases levels of compounds such as acetylcholine, the primary neurotransmitter needed for memory function and “feel good”. As such it is one of the most valuable compounds for relieving depression.
ALC has a variety of properties that include restorative or even protective actions against ageing processes and neurodegeneration. In more simple terms, this means that ALC has a vital role in maintaining brain function as we age. In fact, numerous sound clinical studies have shown that ALC supplementation can help in reducing the mental decline in Alzheimer patients. It is thought that ALC helps slow down the progression of Alzheimer’s because of its cholinergic properties (ability to stimulate the formation of acetylcholine), as well as its ability to support cellular functioning at the mitochondrial level.
Studies show improvement in acquiring and retaining information. It is now known that ALC levels decline with age thereby establishing ALC as a powerful anti-ageing nutrient.
The heart derives 70% of its energy from fat, and fat cannot be burned without carnitine thereby making a crucial heart nutrient. ALC has been found helpful in the treatment of mitral valve prolapse, angina, cardiac arrhythmias, cardiomyopathy, and congestive heart failure. Carnitine is also one of the most important nutrients for lowering cholesterol and triglycerides.
Taking ALC supplements seems to improve sperm motility in men with poorly active sperm, a problem known as asthenozoospermia, Italian researchers report.
With the fatty acids being metabolized by the cells more efficiently, there is naturally an increase in electron flow that goes along with it. Inevitably, that may mean an increase in oxidative stress. Many practitioners add a target anti-oxidant. (NAC Forte or Glutathione (GSH) Liposome).
A typical recommended daily dosage is often 500 mg to 1,000 mg. However, it’s important to realize that ACL is reportedly known for boosting energy levels often within 20 minutes. Therefore it’s best to take before 4 PM.