Diindolylmethane (DIM) is a phytonutrient and plant indole found in cruciferous vegetables including broccoli, Brussel sprouts, cabbage, cauliflower and kale, with potential anti-androgenic and anti-neoplastic activities. DIM provides beneficial estrogen metabolism in both sexes by reducing the levels of 16-alpha hydroxyestrone metabolites and increasing the formation of 2-hydroxyesterone metabolites, resulting in increased antioxidant activity and the inducing of apoptosis in vitro tumour cells.
A wealth of recent studies have documented diindolylmethane (DIM) as one of the most effective phytonutrients in the prophylactic support of breast, prostate, colon and pancreatic cancers.
Diindolylmethane (DIM) is clearly the phytonutrient of choice, clinically activated in a liposome matrix as it by-passes the “liver first pass” and digestive tract directly (ionic ligand) targeting estrogen metabolism.
Researchers have discovered that the metabolism and growth promoting the activity of estrogen is modified by the intake of milligram amounts of dietary indoles from cruciferous vegetables. DIM is formed from its precursor indole, Indole-3-carbinol (I3C), after the enzymatic release of I3C from parent glucosinolates found in all cruciferous vegetables. DIM is unique among all phytonutritionals with regard to its ability to favourably modify estrogen metabolism in the direction of greater 2-hydroxyesterone production.
- Fibroid tumours
- Helps to block the conversion of testosterone to estrogen
- Menopausal symptoms
- Weight problems testosterone to estrogen
- Promotes beneficial estrogen metabolism in both women and men
- Breast, cervical, uterine health
- Prostate health
- Polycystic ovaries