Methylation is a process that occurs @ one billion times per second taking place in the liver during phase two detoxification. Methylation occurs when SAMe (S-adenosine methionine) donates a methyl group, which is then attached to the molecule that is being detoxified. SAMe then becomes homocysteine. Vitamin B6, B12, TMG and folic acid are necessary to reduce homocysteine and keep the methylation processes occurring.
This metabolic process taking place in every cell and vital organ that uses methyl groups to perform functions that include: regulating levels of histamine (which is a key factor in allergic responses), protecting and regulating DNA, promoting detoxification, protein and neuro-transmitter production as well as other brain functions.
Vitamin B12 is a water soluble vitamin necessary for the maintenance of a healthy nervous system and for the metabolic utilisation of fats and proteins. Vitamin B12 is also essential for the synthesis of DNA during cell division and therefore is especially important for rapidly multiplying blood cells. In addition, adequate intake of Vitamin B12, along with Folic Acid and Vitamin B6, encourages healthy serum homocysteine levels, thereby supporting cardiovascular health. TMG (trimethylglycine) works along with Folic Acid, B6, and B12 in the metabolism of homocysteine.